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     220                                 THE ENZYME TREATMENT OF CANCER

 

mixed on injection; that is, I should employ Captain Lambelle’s usual procedure from the start. I should not willingly reduce the dose of trypsin, but rather, if bad effects were noted, increase the amount of amylopsin, even double it. With such doses as these not many injections—not half a dozen—would be exhibited before the injection would be followed shortly by a rigor, which soon passes off, if the patient be in bed. Later in the day— in my experience from 6 p.m. to 9 p.m.—there would be a marked temperature reaction up to 103o F., or even some­times higher. The patient will demand, and should have at all times, abundant water, or barley-water, to drink. The curious feature of this rise in temperature, as I have seen it, is that the skin is dry, and not bathed in perspira­tion. Of course, the pulse along with it is very much quickened. In fact, this treatment would appear to place great demands upon the heart, and it is my own opinion that wherever possible the patient should receive the injections in bed, should be kept there during such temperature-reactions, and as before stated at all times be kept as quiet as possible, refraining from all avoidable physical exertions. In Captain Lambelle’s cases it was noted by him that the effects of the injections—i.e., the constitutional symptoms—lasted from eighteen to twenty-four hours. On the average he gave injections every other day. At times the amount of injection, the number of units, was decreased to one-half or one-quarter of the usual amount of 1,000 tryptic and 2,000 amylolytic units. But, speaking for myself, I should prefer to meet any bad symptoms by an increase of the relative amount of amylopsin, without, if possible, any diminution of the number of tryptic units. Also, as I conceive it, the injections should, if the patient can stand such a course, be exhibited oftener than every other day—as often as four,

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