ROBERT F. CATHCART III, M.D.
ALLERGY, ENVIRONMENTAL & ORTHOMOLECULAR MEDICINE
127 SECOND STREET, SUITE 4
LOS ALTOS, CALIFORNIA 94022
(650) 949-2822
FAX (650) 949-5083

Vitamin C and Cancer

The following are links to the recent research indicating that intravenous vitamin C will be helpful in the treatment of some cancers:

Published online before print September 12, 2005
Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0506390102
Medical Sciences
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues, http://www.pnas.org/cgi/content/abstract/0506390102v1

• Note the statement in this article: "Human pharmacokinetics data indicate that i.v. ascorbic acid (ascorbate) in pharmacologic concentrations could have an unanticipated role in cancer treatment." One has to be in an alternate universe to say something as uninformed as this.  Of course, conventional medicine is in an alternate universe on this subject because they are too busy protecting the drug industry's profits in treating cancer.  See the below references to the work of Hugh Riordan, M.D.
• Animal experimentation to determine the toxicity of ascorbate is a waste of time and money.  First, I have already used 60 to 120 grams of intravenous sodium ascorbate since 1975 in over 2,000 human patients given in 2 to 6 hours without problems. I have given myself 180 grams of sodium ascorbate in 8 hours and felt great.  There are at least 100 or more physicians (mostly members of ACAM) who have also used massive doses of ascorbate.  Because I do not give these IVC's in a hospital setting I have not used it is patients with kidney failure.  I have used oral ascorbic acid in the treatment of 2 patients with hemachromatosis.
• Secondly, only man, higher monkeys, Guinea pig and the African fruit eating bat do not make ascorbate.  If you use ascorbate on other animals that make their own ascorbate you may make them make less ascorbate than you give them so as to produce negative paradoxical results.  This is a ploy that should delay research on massive doses of C for years and preserve the orthodox ignorance on the subject.
• Finally, what is this calling 10 grams a day large doses?  Anyone who says something as stupid as this has no knowledge of massive doses of C.  It is a very sneaky ploy to say that those of us who claim to cure something with massive doses of ascorbate and then do an experiment with ridiculously small doses of ascorbate and call them large doses.  This produces negative results and delays progress and preserves the profits of the drug industry for another generation.
• Never reference Pauling, Klenner, Stone, Riordan, or myself who have been writing about massive doses of C for years. If these works are not referenced is this not plagiarism?   That would break readers out of their little uninformed universe that can spend 100s of millions of dollars on research and never find anything useful.  Viva la drug industry.  This is genocide but who cares.

This was picked up by the popular press:

Study: Vitamin C May Fight Cancer: FOXNews.com, WebMD

In Extremis: First Aid for Advanced Cancer

• A very interesting link.  There are cited extensive studies on the compatibility of ascorbate with many substances that might be given IV.

IV Ascorbate Used in the Treatment of Cancer

Intravenous Vitamin C is 

Selectively Toxic to Cancer Cells,

Orthomolecular Medicine News Service, 

September 22, 2005, 

Hugh Riordan, M.D.,

The Center For The Improvement Of Human Functioning International

Vitamin C Research Papers

Orthomolecular Oncology Review: Ascorbic Acid and Cancer 25 years Later
By Michael J. González, Jorge R. Miranda-Massari, Edna M. Mora, Angelik Guzmán, Neil H. Riordan, Hugh D. Riordan, Joseph J. Casciari, James A. Jackson, and Angel Romá-Franco, from Integrative Cancer Therapies 4(1); 2005 pp.32-44

Intravenous Ascorbic Acid: Protocol for its Application and Use
By Hugh D. Riordan, Ronald E. Hunninghake, Neil H. Riordan, James A. Jackson, Xiao LongMeng, Paul Taylor, etal, from Puerto Rico Health Sciences Journal (2003) 22:3, 287-290

The Effect of Alternating Magnetic Field Exposure and Vitamin C on Cancer Cells
By N. Mikirova, J.A. Jackson, J.P. Casciari and H.D. Riordan, from Journal of Orthomolecular Medicine (2001) 3, 177-182

Cytotoxicity of Ascorbate, Lipoic Acid, and Other Antioxidants In Hollow Fibre In Vitro Tumours
By J.P. Casciari, N.H. Riordan, T.L. Schmidt, XL Meng, J.A. Jackson and H.D. Riordan, from British Journal of Cancer (2001) 84:11, 1544-1550

Clinical and Experimental Experiences with Intravenous Vitamin C
By N.H. Riordan, H.D. Riordan, J.A. Jackson and J.P. Casciari, from Journal of Orthomolecular Medicine (2000) 15:4, 201-213

Different Fatty Acid Composition Between Normal and Malignant Cell Lines
By X.L. Meng, N.H. Riordan, H.D. Riordan, J.A. Jackson, et al, from BioMedicina, (1999) 2:4, 5-7

Rethinking Vitamin C and Cancer: An Update on Nutritional Oncology
By M.J. Gonzalez, E. Mora, N.H. Riordan, H.D. Riordan and P. Mojica, from Cancer Prevention International (1998) 3, 215-224

Intravenous Ascorbate as a Chemotherapeutic and Biologic Response Modifying Agent
Bio-Communications Research Institute (1997)

Intravenous Vitamin C in a Terminal Cancer Patient
By N.H. Riordan, J.A. Jackson and H.D. Riordan, from Journal of Orthomolecular Medicine (1996) 11, 80-82

High-Dose Intravenous Vitamin C and Long-Time Survival of a Patient with Cancer of Head of the Pancreas
By J.A. Jackson, H.D. Riordan, R.E. Hunninghake and N.H. Riordan, from Journal of Orthomolecular Medicine (1995) 10, 87-88

Intravenous Ascorbate as a Tumor Cytotoxic Chemotherapeutic Agent
By N.H. Riordan, H.D. Riordan, X. Meng, Y. Li and J.A. Jackson, from Medical Hypotheses (1995) 44, 207-213

Case Study: High-Dose Intravenous Vitamin C in the Treatment of a Patient with Adenocarcinoma of the Kidney
By H.D. Riordan, J.A. Jackson and Mavis Schultz, from Journal of Orthomolecular Medicine (1990) 5:1, 5-7